cGMP · 21 CFR Part 11 · ISO 13485 · ISO 14971

The eQMS your operators actually use.

Kalova is the document and quality system for regulated process manufacturing. Documents, change control, deviations, CAPA, risk, complaints, audits, equipment, training — one platform, audit-ready, with AI in every workflow.

21 CFR Part 11 e-signatures ALCOA+ audit trail Validated install (IQ/OQ)
kalova.io/chat/acme
What's the gowning sequence for Class B?

Class B gowning per QA-SOP-014: hand wash → sterile coverall → hood → goggles → mask → second glove pair. Verify integrity at each step; record initials in the gowning log.

Sources01QA-SOP-014 Aseptic gowning v6.pdf
Line clearance failed twice on Line 3 — what now?

Two consecutive line-clearance failures require a Tier-2 deviation (NCR-002). Stop the line, page QA on-call, isolate the lot, and document with photos in the deviation record.

Sources01QA-SOP-007 Line clearance v4.pdf02NCR-002 Deviation handling.pdf
21 CFR
Part 11 e-signatures, end-to-end
100%
Of answers cite a controlled SOP
< 1 day
Inspection-bundle export, ready to hand to FDA
ALCOA+
Tamper-evident audit trail on every record

Built for process manufacturing

One platform for documents, training, and quality.

Pharma, biotech, medical device, food & beverage, specialty chemicals — anywhere a regulator cares whether the operator followed the procedure at the effective revision.

Production operators

Operators ask plain questions on the floor — gowning, line clearance, batch changeover, deviation handling — and get the SOP answer cited at the current effective revision.

  • Floor-friendly on iPad and shop-floor PCs
  • Always answers from the controlled SOP
  • Says "not in the procedure" instead of guessing

Quality assurance

Author, route, and e-sign SOPs with full Part 11 lifecycle. Approvals, periodic review, change control, and the audit chain — all tamper-evident.

  • Author/approver separation enforced
  • Reason-for-change captured at every revision
  • One-click inspection bundle export

Training & qualification

Build courses with video, image, PDF, and quiz lessons. Assign by labor class. Track read-and-acknowledge and competency sign-offs against the training matrix.

  • Auto-assign retraining when the SOP changes
  • iPad-friendly course player for the floor
  • Training records ready for inspection

How it works

From PDFs to answers in three steps.

01

Migrate your SOP library

Drop in PDFs, Word, batch records, training videos, work-instruction images. We OCR, chunk, and stamp every revision. Lifecycle, owner, sensitivity, and review cadence are captured at intake.

QA-SOP-014 Aseptic gowning v6.pdfEffective
MFG-WI-022 Line clearance v3.docxEffective
Bosch SHX final test.mp4Processing
02

Train and qualify your operators

Build courses from the SOP — modules, video lessons, knowledge checks, e-signed attestations. Assign by labor class. Auto-retrain when an SOP revises.

Course
Aseptic gowning · Class B
Assigned to
Operator I, QA Specialist
17 of 18 qualified
03

Stay inspection-ready

When the auditor walks in, you don’t scramble. Every SOP has its lifecycle, every signature its meaning, every training record its e-signed proof — exportable as one bundle.

Show the FDA the signed-and-effective gowning SOP plus all training records.
Inspection bundle ready: SOP v6 (effective), 18 training acks, 4 deviations linked.
Audit chain: verified

The full eQMS, in one platform

Nine modules. One audit trail.

Most QMS vendors stop at document control. Kalova covers the whole quality system — every module wired into the same audit chain, with AI in the slot where humans get tired.

Documents & SOPs
Lifecycle, versioning, e-sign, periodic review
Change control
AI impact assessment, dual-signature gates
Deviations / NCR
AI 5-Whys, severity classification, CAPA linkage
CAPA
Action plans, owner sign-off, effectiveness checks
Risk (ISO 14971)
Hazard chains, AI hazard + control suggester
Customer complaints
AI severity + 21 CFR 803 / EU Vigilance reportability
Internal audits
AI checklist gen, finding tracking, CAPA-linked
Equipment & calibration
OOT auto-opens deviation, due-date tracking
Recurrence trending
AI clusters root causes, surfaces systemic gaps

What's different about Kalova

Audit-defensible AI, on top of a real eQMS.

Plenty of QMS platforms can store an SOP. Plenty of AI tools can answer questions. Kalova is the only place both happen at the same time — every answer cites the controlled document at the effective revision, with a hash-chained audit trail behind it.

Citation-grade answers

Every operator question is answered from your effective SOPs, with the source passage, version, and lifecycle state visible inline. If the procedure doesn't cover it, the bot says so — instead of guessing.

  • Inline [Source N] references on every claim
  • Numeric values verified against the source
  • Term-fidelity guard catches paraphrased artifact names

21 CFR Part 11 lifecycle

Author → review → approve → effective → periodic review → supersede. E-signatures with reason-for-change, hash-chained audit log, ALCOA+ posture. Built around how regulated companies actually run a QMS.

  • Author / approver separation enforced
  • Tamper-evident audit chain (verifiable on demand)
  • Inspection bundle exports in seconds

Where the work happens

Web, Slack, WhatsApp, embedded public chat. Operators don't have to learn another system — they ask in the channel they already use. QA gets the audit trail in one dashboard.

  • WhatsApp + Slack + web + embed
  • Vendor portal for CAPA & audit findings
  • Per-tenant branding and public chat URL

Pricing

Priced to match your site, not your seat count.

Kalova is built for regulated process manufacturing — pharma, biotech, medical device, food & beverage, specialty chemicals. Every deployment is configured for your quality system, your SOP library, your training matrix, and your inspection posture. We’ll scope a plan in one call.

Included
Validated install & IQ/OQ packet
Included
21 CFR Part 11 e-signature workflow
Included
Inspection-mode bundle export

Sandbox tenants are free for evaluation. Production tenants are quoted per site after a scoping call.

Stop running your QMS out of a shared drive.

Kalova is a real quality system that operators want to use and inspectors are happy to see. Book a scoping call and we’ll have a tenant ready for you to evaluate in days.